Telemeres and Longevity
Longevity appears to be controlled at the end
of the chromosomes by a section called telomeres. The telomeres contain subunits
of DNA that initially contain about 10,000 bases at birth that gradually decreases
in length to a point where senility starts and terminates in death.
Research has developed an agent that activates the enzyme telomerase which
is believed to increase telomere length. This agent is derived from the root
of the plant Astragalus. The condition of the telomeres is a reflection on
the status of the cells. Healthy telomere; healthy cells. However, as cells
continue to divide the telomeres get shorter. As one reaches the 70s and 80s
or develop a serious chronic disease the telomeres will become very short
; cell division slows up and death may soon follow.
Scientists for many years have been working with an enzyme called telomerase
in an attempt to immortalize human cells. In laboratory cultures telomerase
has been able to maintain longevity in all types of cells such as colon, skin,
retina and breast.
The hope is to possibly increase longevcity and slow down the aging process
and possibly reverse the effects of serious debilitating diseases.
The doctor and patient must evaluate the risk/benefit of using such an agent
to increase the length of telomeres. It will take many more years of research
to determine the efficacy of such treatment. The patient who is over the age
of fifty years or the very elderly facing death might be considered potential
candidates for such treatment when they are fully informed. Younger patients
faced with the onset of a serious chronic disease (heart disease, COPD, diabetes
type 1, chronic kidney disease, Crohn’s disease, ulcerative colitis, Parkinson,
Alzheimer’s, ALS, multiple sclerosis) could be also candidates for this therapy.
The medication can be taken by mouth. In some cases the patient’s cells could
be cultured with a gene for telomerase and then re-administered into the patient
for a short term therapy.
Persons interested in getting further information about telomeres/telomerase
and cost of treatment should contact us by e-mail at info@stemcellregenmed.com
or by calling 1-888-620-0411
Anti-Aging Medicine
((941)388-2277
(888)620-0411
info@anti-agingmedicine.com
drf@anti-agingmedicine.com
Burton Feinerman, M.D.
Graduate; New York Medical College
Fellowship; Mayo Clinic, Rochester, Minnesota
Specialty; Anti-aging medicine
American Society of Hematology and Stem Cells
International Society for Cellular Therapy
Society of Apheresis
Society for Bone Marrow and Blood Transplants
Society for Cranial Transplants and Brain Repair
Society for Cardiac Translational Research